⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13010612 | 1.00 | ALDH1A1 (0.55) | — | |
| SCHEMBL11150202 | 0.97 | — | — | |
| SCHEMBL22746212 | 0.90 | — | — | |
| SCHEMBL28302464 | 0.86 | ALDH1A1 (0.42) | — | |
| SCHEMBL3948862 | 0.73 | ALDH1A1 (0.93) | — | |
| SCHEMBL3947407 | 0.73 | ALDH1A1 (0.93) | — | |
| SCHEMBL2323473 | 0.73 | ALDH1A1 (0.93) | — | |
| SCHEMBL3947402 | 0.73 | ALDH1A1 (0.93) | — | |
| SCHEMBL3948084 | 0.73 | ALDH1A1 (0.93) | — | |
| SCHEMBL8024247 | 0.73 | ALDH1A1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344634-A | Fluorine-containing formaldehyde-based piperidine type anion exchange membrane and preparation method thereof | 大连理工大学 | 2024-07-16 | — | — | CN | claimed |
| CN-118344634-A | Fluorine-containing formaldehyde-based piperidine type anion exchange membrane and preparation method thereof | 大连理工大学 | 2024-07-16 | — | — | CN | disclosed |
| EP-4228650-A1 | INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF | Epirium Bio Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| EP-4093385-A1 | PGDH INHIBITORS AND METHODS OF MAKING AND USING | Myoforte Therapeutics Inc. (US) | 2022-11-30 | — | — | EP | disclosed |
| WO-2022082009-A1 | INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF | EPIRIUM BIO INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | disclosed |
| US-7569587-B2 | Antibacterial mutilins | NABRIVA THERAPEUTICS AG (AT) | 2009-08-04 | — | — | US | disclosed |
| US-20070161674-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2007-07-12 | — | — | US | disclosed |