Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027801 | 0.82 | RAB9A (0.57) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL9979785 | 0.79 | CA12 (0.62) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL707407 | 0.78 | CA12 (0.67) | RAB9AMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL4848144 | 0.77 | CTNNB1 (0.56) | RAB9ANPC1CLK1MAPTALDH1A1 | |
| SCHEMBL1960994 | 0.77 | CA12 (0.65) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL15800506 | 0.76 | CTNNB1 (0.52) | RAB9ANPC1CLK1MAPTALDH1A1 | |
| SCHEMBL1464834 | 0.75 | MAPK1 (0.69) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL12338713 | 0.74 | RAB9A (0.56) | RAB9ANPC1CLK1MAPTALDH1A1 | |
| SCHEMBL2761208 | 0.74 | CA12 (0.57) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL18987822 | 0.73 | MAOB (0.43) | RAB9ANPC1CLK1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222174-B1 | IMIDAZOL-4-YLMETHANOLS USED AS INHIBITORS OF STEROID C17-20 LYASE | TAKEDA PHARMACEUTICAL (JP) | 2009-05-27 | — | — | EP | disclosed |
| US-6649643-B1 | Antitumor, anticarcinogenic, and antimetastasis agents; benign prostatic hyperplasia, alopecia, endometriosis, uterine myoma, hirsutism, virilism, precocious puberty, mastopathy, and polycystic overay syndrome treatment | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-11-18 | — | — | US | disclosed |