⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941926 | 0.81 | — | — | |
| SCHEMBL4641210 | 0.81 | — | — | |
| SCHEMBL3880423 | 0.79 | — | — | |
| SCHEMBL10432238 | 0.78 | TSHR (0.35) | — | |
| SCHEMBL10742171 | 0.77 | — | — | |
| SCHEMBL2987089 | 0.76 | TSHR (0.34) | — | |
| SCHEMBL7328517 | 0.75 | — | — | |
| SCHEMBL8507858 | 0.75 | THRB (0.35) | — | |
| SCHEMBL7770477 | 0.75 | — | — | |
| SCHEMBL3168705 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103274988-B | 3-(cyano group-p-nitrobenzoyl support group)-2-indolone derivatives and preparation method and use thereof | HEBEI UNIVERSITY (CN) | 2016-04-13 | — | — | CN | claimed |
| CN-103274988-A | 3-(cyano-p-nitrobenzene methylene)-2-indolone derivative and synthesis method and application thereof | UNIV HEBEI | 2013-09-04 | — | — | CN | claimed |
| EP-0851899-A1 | BENZOTHIOPHENE-2-CARBOXAMIDE-S,S-DIOXIDES FOR USE IN ANTI-FOULING APPLICATIONS | BAYER AG (DE) | 1998-07-08 | — | — | EP | claimed |
| WO-1997011131-A1 | BENZOTHIOPHENE-2-CARBOXAMIDE-S,S-DIOXIDES FOR USE IN ANTI-FOULING APPLICATIONS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-27 | — | — | WO | claimed |
| EP-0355597-A1 | Substituted dioxolanylethylamines, process for their preparation, their use in pesticides, and intermediates | BAYER AG (DE) | 1990-02-28 | — | — | EP | claimed |
| CN-103274988-B | 3-(cyano group-p-nitrobenzoyl support group)-2-indolone derivatives and preparation method and use thereof | HEBEI UNIVERSITY (CN) | 2016-04-13 | — | — | CN | disclosed |
| CN-103274988-A | 3-(cyano-p-nitrobenzene methylene)-2-indolone derivative and synthesis method and application thereof | UNIV HEBEI | 2013-09-04 | — | — | CN | disclosed |
| CN-102686556-A | Opening of lactones and lactams | NOVARTIS AG | 2012-09-19 | — | — | CN | disclosed |
| CN-102260188-A | organic compounds | — | 2011-11-30 | — | — | CN | disclosed |
| EP-1717226-B1 | 2,7-SUBSTITUTED 5-AMINO-4-HYDROXY-8-(1H-INDOL-5-YL)-OCTAN AMIDE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | SPEEDEL EXPERIMENTA AG (CH) | 2009-01-21 | — | — | EP | disclosed |
| EP-1802608-A1 | QUINAZOLINE DERIVATIVES FOR USE AGAINST CANCER | AstraZeneca AB (SE) | 2007-07-04 | — | — | EP | disclosed |
| US-20070066604-A1 | Diaminoalcohols as therapeutic compounds | SPEEDEL EXPERIMENTA AG (CH) | 2007-03-22 | — | — | US | disclosed |
| EP-0689507-A1 | INK RIBBONS CONTAINING COMPOUNDS ABSORBING IN THE IR REGION | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-03 | — | — | EP | disclosed |
| EP-0656929-A1 | USE OF COMPOUNDS WHICH ABSORB AND/OR FLUORESCE IN THE I/R RANGE AS MARKERS FOR LIQUIDS. | BASF AG (DE) | 1995-06-14 | — | — | EP | disclosed |
| EP-0630354-A1 | MOLECULAR SIEVES CONTAINING AZO DYES. | BASF AG (DE) | 1994-12-28 | — | — | EP | disclosed |
| WO-1994021471-A1 | INK RIBBONS CONTAINING COMPOUNDS ABSORBING IN THE IR REGION | BASF AKTIENGESELLSCHAFT (DE) | 1994-09-29 | — | — | WO | disclosed |
| WO-1993017965-A1 | MOLECULAR SIEVES CONTAINING AZO DYES | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-16 | — | — | WO | disclosed |
| EP-0351615-A1 | Process for the preparation of 4-alkoxy-2-hydroxybenzophenone-5-sulfonic acids | BASF Aktiengesellschaft (DE) | 1990-01-24 | — | — | EP | disclosed |
| US-4837310-A | LIGHTFAST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-06 | — | — | US | disclosed |
| US-4069323-A | INHIBITION AND SUPPRESSION OF THROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1978-01-17 | — | — | US | disclosed |