Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030636 | 0.80 | FFAR1 (0.53) | FFAR1PPARGRAB9ASMN1; SMN2PPARD | |
| SCHEMBL4026189 | 0.79 | FFAR1 (0.50) | FFAR1PPARGPPARA | |
| SCHEMBL1508341 | 0.79 | FFAR1 (0.47) | FFAR1PPARG | |
| SCHEMBL1508339 | 0.79 | FFAR1 (0.47) | FFAR1PPARG | |
| SCHEMBL4029325 | 0.77 | AR (0.47) | ARNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL5691423 | 0.75 | AR (0.56) | FFAR1ARNPC1HPGDRAB9A | |
| SCHEMBL4025989 | 0.75 | PPARG (0.45) | FFAR1PPARGHPGDPPARA | |
| SCHEMBL874437 | 0.74 | AR (0.62) | FFAR1ARNPC1HPGDRAB9A | |
| SCHEMBL4030089 | 0.74 | PPARG (0.56) | PPARGPPARDPPARA | |
| SCHEMBL3187746 | 0.73 | MGLL (0.59) | FFAR1ARNPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-B1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2009-01-07 | — | — | EP | claimed |