Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943978 | 0.93 | RAB9A (0.58) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL3942490 | 0.93 | RAB9A (0.58) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL3944015 | 0.93 | RAB9A (0.58) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL3941454 | 0.93 | RAB9A (0.58) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL4197663 | 0.93 | RAB9A (0.58) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL4029173 | 0.88 | MAPT (0.47) | RAB9ANPC1MEN1ALDH1A1KMT2A | |
| SCHEMBL4208314 | 0.86 | RAB9A (0.50) | RAB9ANPC1HDAC1HDAC6MEN1 | |
| SCHEMBL4206843 | 0.86 | RAB9A (0.48) | RAB9ANPC1HDAC1HDAC6ACKR3 | |
| SCHEMBL4212851 | 0.85 | RAB9A (0.49) | RAB9ANPC1HDAC1HDAC6MEN1 | |
| SCHEMBL3941064 | 0.85 | RAB9A (0.57) | RAB9ANPC1HDAC1HDAC6ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |