Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 10/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025605 | 0.88 | DRD3 (0.35) | MKNK1DRD3PGRADORA3CHRM1 | |
| SCHEMBL4025893 | 0.88 | DRD3 (0.37) | MKNK1DRD3PGRADORA3CHRM1 | |
| SCHEMBL4031259 | 0.87 | MKNK1 (0.38) | MKNK1DRD3PGRADORA3CHRM1 | |
| SCHEMBL4029566 | 0.82 | DRD3 (0.38) | MKNK1DRD3PGRADORA3CHRM1 | |
| SCHEMBL4026186 | 0.78 | PGR (0.38) | DRD3PGRADORA3CHRM1TBXA2R | |
| SCHEMBL4031253 | 0.78 | DRD3 (0.39) | MKNK1DRD3PGRADORA3CHRM1 | |
| SCHEMBL4025890 | 0.77 | DRD3 (0.41) | MKNK1DRD3PGRADORA3CHRM1 | |
| SCHEMBL1338143 | 0.76 | PGR (0.61) | DRD3PGRADORA3CHRM1TBXA2R | |
| SCHEMBL6076338 | 0.76 | PGR (0.53) | DRD3PGRADORA3CHRM1TBXA2R | |
| SCHEMBL4025892 | 0.76 | DRD3 (0.44) | DRD3PGRADORA3CHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-B1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2009-01-07 | — | — | EP | claimed |