Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 2/20 | 0.32 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034202 | 0.89 | PPARG (0.52) | PPARGPPARDPPARAACHEEPHX2 | |
| SCHEMBL4034567 | 0.89 | PPARG (0.53) | PPARGPPARDPPARAACHEEPHX2 | |
| SCHEMBL4033028 | 0.85 | PPARG (0.54) | PPARGPPARDPPARAACHEEPHX2 | |
| SCHEMBL4799615 | 0.84 | PPARG (0.51) | PPARGPPARDPPARAACHEEPHX2 | |
| SCHEMBL4030846 | 0.84 | PPARD (0.69) | PPARGPPARDPPARAACHEEPHX2 | |
| SCHEMBL4034274 | 0.83 | PPARG (0.52) | PPARGPPARDPPARAACHE | |
| SCHEMBL4030150 | 0.81 | PPARG (0.52) | PPARGPPARDPPARAACHEHSD17B10 | |
| SCHEMBL4028015 | 0.80 | PPARG (0.54) | PPARGPPARDPPARAACHEKDM4E | |
| SCHEMBL4024977 | 0.79 | PPARD (0.54) | PPARGPPARDPPARAUSP1WDR48 | |
| SCHEMBL3393036 | 0.79 | PPARD (0.62) | PPARGPPARDPPARAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445258-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2009-06-24 | — | — | EP | disclosed |
| US-7402597-B2 | Activator of peroxisome proliferator-activated receptor δ | NIPPON CHEMIPHAR CO., LTD (JP) | 2008-07-22 | — | — | US | disclosed |
| US-20070027196-A1 | Activator of peroxisome proliferator-activated receptor delta | SAKUMA SHOGO | 2007-02-01 | — | — | US | disclosed |
| US-7119104-B2 | Activator of peroxisome proliferator-activated receptor delta | NIPPON CHEMIPHAR, CO., LTD. (JP) | 2006-10-10 | — | — | US | disclosed |
| US-20050096363-A1 | Activator of peroxisome proliferator-activated receptor delta | NIPPON CHEMIPHAR CO., LTD. (JP) | 2005-05-05 | — | — | US | disclosed |
| EP-1445258-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027196-A1 | Activator of peroxisome proliferator-activated receptor delta | PPARA, PPARG, PPARD | PPARG 2/4885PPARD 3/4885PPARA 1/4885 |
| US-20050096363-A1 | Activator of peroxisome proliferator-activated receptor delta | PPARA, PPARG, PPARD | PPARG 2/4885PPARD 3/4885PPARA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.