Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | NPY1R | P25929 | 2/20 | 0.37 |
| ▸ | NPY2R | P49146 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027388 | 0.89 | CHRM3 (0.41) | CHRM3SMN1; SMN2LMNAL3MBTL1SLC6A4 | |
| SCHEMBL4033425 | 0.84 | TDP1 (0.42) | CHRM3TDP1SUCNR1SMN1; SMN2NPSR1 | |
| SCHEMBL4028060 | 0.83 | TDP1 (0.39) | CHRM3TDP1SUCNR1SMN1; SMN2NPSR1 | |
| SCHEMBL4026961 | 0.80 | CHRM3 (0.48) | CHRM3TDP1NPSR1CHRM2CHRM1 | |
| SCHEMBL4029697 | 0.80 | CHRM3 (0.43) | CHRM3TDP1SMN1; SMN2NPSR1NPY1R | |
| SCHEMBL4029121 | 0.75 | QPCT (0.41) | CHRM3SMN1; SMN2LMNASLC6A4SLC6A3 | |
| SCHEMBL4027784 | 0.72 | CHRM3 (0.39) | CHRM3SMN1; SMN2LMNAL3MBTL1CHRM2 | |
| SCHEMBL4026785 | 0.70 | CHRM3 (0.44) | CHRM3SMN1; SMN2LMNASLC6A4SLC6A3 | |
| SCHEMBL4025143 | 0.70 | CHRM3 (0.50) | CHRM3LMNAALDH1A1KDM4E | |
| SCHEMBL4024550 | 0.69 | CHRM3 (0.52) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252140-B1 | PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-13 | — | — | EP | claimed |