Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | NPY2R | P49146 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027784 | 0.90 | CHRM3 (0.39) | SMN1; SMN2LMNAL3MBTL1CHRM3SLC6A4 | |
| SCHEMBL4033425 | 0.83 | TDP1 (0.42) | TDP1SMN1; SMN2NPY1RNPY2RLMNA | |
| SCHEMBL4030948 | 0.83 | CHRM3 (0.40) | TDP1SMN1; SMN2NPY1RNPY2RLMNA | |
| SCHEMBL4029697 | 0.79 | CHRM3 (0.43) | TDP1SMN1; SMN2NPY1RNPY2RLMNA | |
| SCHEMBL4031163 | 0.77 | CHRM3 (0.46) | TDP1SMN1; SMN2NPY1RNPY2RLMNA | |
| SCHEMBL4029121 | 0.74 | QPCT (0.41) | SMN1; SMN2LMNACHRM3SLC6A4SLC6A3 | |
| SCHEMBL4027388 | 0.72 | CHRM3 (0.41) | SMN1; SMN2LMNAL3MBTL1CHRM3SLC6A4 | |
| SCHEMBL4026785 | 0.70 | CHRM3 (0.44) | SMN1; SMN2LMNACHRM3SLC6A4SLC6A3 | |
| SCHEMBL21423850 | 0.70 | CHRM3 (0.46) | LMNANPSR1L3MBTL1CHRM3CHRM2 | |
| SCHEMBL29419144 | 0.69 | TDP1 (0.53) | TDP1SMN1; SMN2NPY1RNPY2RLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252140-B1 | PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-13 | — | — | EP | claimed |