Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024428 | 0.80 | NPC1 (0.43) | EGFRSRCKDM4ELMNAALOX15 | |
| SCHEMBL5375493 | 0.74 | CNR2 (0.42) | POLB | |
| SCHEMBL13073331 | 0.73 | CA12 (0.61) | POLB | |
| SCHEMBL14861105 | 0.73 | CA12 (0.61) | POLB | |
| SCHEMBL6961215 | 0.73 | CA12 (0.61) | POLB | |
| SCHEMBL28662112 | 0.72 | MEN1 (0.43) | EGFRKDM4EPOLBMAPT | |
| Hydrochloric Acid SCHEMBL7759019 | 0.72 | CA12 (0.60) | POLB | |
| Hydrochloric Acid SCHEMBL7206635 | 0.72 | CA12 (0.60) | POLB | |
| SCHEMBL4024423 | 0.71 | L3MBTL1 (0.50) | L3MBTL1MAPTALDH1A1 | |
| SCHEMBL19710389 | 0.70 | POLB (0.55) | POLBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513811-B1 | NON-PEPTIDIC BRS-3 AGONISTS | SOLVAY PHARM GMBH (DE) | 2009-04-08 | — | — | EP | disclosed |