Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.63 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.63 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.62 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.62 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.62 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.62 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031132 | 1.00 | KDM4E (0.65) | KDM4ELMNALTB4RLTB4R2PTGER3 | |
| SCHEMBL4029676 | 0.95 | KDM4E (0.65) | KDM4ELMNALTB4RLTB4R2PTGER3 | |
| SCHEMBL4029671 | 0.95 | KDM4E (0.65) | KDM4ELMNALTB4RLTB4R2PTGER3 | |
| SCHEMBL344657 | 0.92 | PTGER3 (0.68) | KDM4ELMNALTB4RLTB4R2PTGER3 | |
| SCHEMBL344658 | 0.92 | PTGER3 (0.68) | KDM4ELMNALTB4RLTB4R2PTGER3 | |
| SCHEMBL6036139 | 0.89 | HDAC8 (0.65) | KDM4ELMNALTB4RLTB4R2PTGER3 | |
| SCHEMBL6036142 | 0.89 | HDAC8 (0.65) | KDM4ELMNALTB4RLTB4R2PTGER3 | |
| SCHEMBL4032216 | 0.83 | TUBB1 (0.52) | KDM4ELMNAPKMSMN1; SMN2PPARG | |
| SCHEMBL344776 | 0.83 | PTGER4 (0.70) | KDM4ELMNALTB4RLTB4R2PTGER3 | |
| SCHEMBL344775 | 0.83 | PTGER4 (0.70) | KDM4ELMNALTB4RLTB4R2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357115-B1 | ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2009-06-17 | — | — | EP | disclosed |
| US-7238716-B2 | Alkanoic acid derivatives process for their production and use thereof | TAKEDA PHARMACEUTICALS COMPANY LIMITED (JP) | 2007-07-03 | — | — | US | disclosed |
| US-20040058965-A1 | Alkanoic acid derivatives process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-25 | — | — | US | disclosed |
| EP-1357115-A1 | ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058965-A1 | Alkanoic acid derivatives process for their production and use thereof | GPR119, ACOX1, ALK | KDM4E 570/4885LMNA 1867/4885LTB4R 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.