Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | REN | P00797 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PEPD | P12955 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027303 | 1.00 | ACE (0.43) | ACECYP1A2CYP2C19RENLMNA | |
| SCHEMBL28235237 | 0.94 | SMN1; SMN2 (0.46) | ACECYP1A2CYP2C19RENLMNA | |
| SCHEMBL8768615 | 0.81 | ACE (0.44) | ACECYP1A2CYP2C19RENLMNA | |
| SCHEMBL1860361 | 0.81 | ACE (0.44) | ACECYP1A2CYP2C19RENLMNA | |
| SCHEMBL3721761 | 0.79 | ACE (0.43) | ACECYP1A2CYP2C19RENLMNA | |
| SCHEMBL3771340 | 0.79 | ACE (0.45) | ACECYP1A2CYP2C19RENLMNA | |
| SCHEMBL2275704 | 0.79 | ALDH1A1 (0.47) | ACECYP1A2CYP2C19RENLMNA | |
| SCHEMBL28452245 | 0.79 | ACE (0.43) | ACECYP1A2CYP2C19RENLMNA | |
| SCHEMBL151570 | 0.79 | ALDH1A1 (0.47) | ACECYP1A2CYP2C19RENLMNA | |
| SCHEMBL7048989 | 0.79 | ACE (0.43) | ACECYP1A2CYP2C19RENLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100360-A1 | STABILIZATION OF THE COLLAGEN TRIPLE HELIX BY O-METHYLATION OF HYDROXYPROLINE RESIDUES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-08-13 | — | — | WO | disclosed |