Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 14/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023844 | 0.90 | PTGES (0.45) | PTGESPPARGPPARASERPINE1PTPN5 | |
| SCHEMBL4027503 | 0.84 | PTGES (0.71) | PTGESPPARGPPARASERPINE1 | |
| SCHEMBL4021807 | 0.82 | PTGES (0.60) | PTGESPPARGPPARASERPINE1 | |
| Hydrochloric Acid SCHEMBL4021808 | 0.81 | PTGES (0.59) | PTGESPPARGPPARASERPINE1 | |
| SCHEMBL4914921 | 0.81 | PTGES (0.63) | PTGESPPARGPPARASERPINE1 | |
| SCHEMBL4024171 | 0.80 | PTGES (0.58) | PTGESPPARGPPARASERPINE1 | |
| SCHEMBL4021862 | 0.79 | PTGES (0.56) | PTGESPPARGPPARASERPINE1PTPN5 | |
| SCHEMBL4027202 | 0.78 | PTGES (0.64) | PTGESPPARGPPARASERPINE1 | |
| SCHEMBL4025309 | 0.78 | PTGES (0.83) | PTGESPPARGPPARASERPINE1 | |
| SCHEMBL334036 | 0.77 | PTGES (0.49) | PTGESPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765775-B1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-04-29 | — | — | EP | disclosed |
| US-20080146616-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146616-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, PTGS1, PTGER1 | PTGES 4/4885PPARG 693/4885PPARA 1116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.