Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.53 |
| ▸ | SRC | P12931 | 8/20 | 0.52 |
| ▸ | KDR | P35968 | 12/20 | 0.51 |
| ▸ | CSK | P41240 | 3/20 | 0.51 |
| ▸ | TEK | Q02763 | 3/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024202 | 0.91 | SRC (0.56) | EGFRSRCKDRCSKTEK | |
| SCHEMBL4020660 | 0.86 | EGFR (0.53) | EGFRSRCKDRCSKTEK | |
| SCHEMBL4026562 | 0.82 | EGFR (0.53) | EGFRSRCKDRCSKTEK | |
| SCHEMBL4030245 | 0.80 | SRC (0.54) | EGFRSRCKDRCSKTEK | |
| SCHEMBL4027299 | 0.80 | SRC (0.56) | EGFRSRCKDRCSKTEK | |
| SCHEMBL4025139 | 0.79 | SRC (0.55) | EGFRSRCKDRCSKTEK | |
| SCHEMBL4027347 | 0.79 | EGFR (0.52) | EGFRSRCKDRCSKTEK | |
| SCHEMBL4021449 | 0.78 | SRC (0.54) | EGFRSRCKDRCSKTEK | |
| SCHEMBL4023711 | 0.78 | KDR (0.53) | EGFRSRCKDRCSKTEK | |
| SCHEMBL6164850 | 0.77 | SRC (0.50) | EGFRSRCKDRCSKTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1528925-B1 | QUINAZOLINE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2009-04-22 | — | — | EP | claimed |