Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031065 | 0.91 | SLC9A3 (0.62) | SLC9A3 | |
| SCHEMBL4038411 | 0.91 | L3MBTL1 (0.59) | SLC9A3SMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL4032721 | 0.90 | SLC9A3 (0.65) | SLC9A3 | |
| SCHEMBL4025796 | 0.89 | SLC9A3 (0.63) | SLC9A3 | |
| SCHEMBL4035736 | 0.89 | SLC9A3 (0.63) | SLC9A3 | |
| SCHEMBL4029541 | 0.88 | SLC9A3 (0.61) | SLC9A3 | |
| SCHEMBL4029470 | 0.88 | SLC9A3 (0.55) | SLC9A3 | |
| SCHEMBL4025508 | 0.82 | SLC9A3 (0.68) | SLC9A3 | |
| SCHEMBL4028711 | 0.82 | SLC9A3 (0.68) | SLC9A3 | |
| SCHEMBL4029010 | 0.81 | SLC9A3 (0.49) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453810-B1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AS MEDICAMENTS, IN ADDITION TO A MEDICAMENT CONTAINING SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-03-18 | — | — | EP | claimed |
| EP-1453810-B1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AS MEDICAMENTS, IN ADDITION TO A MEDICAMENT CONTAINING SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-03-18 | — | — | EP | disclosed |