Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031866 | 1.00 | STING1 (0.39) | STING1KDM1AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3942217 | 0.85 | MAPT (0.43) | STING1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4035465 | 0.84 | KMT2A (0.42) | MAPTKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL4035456 | 0.84 | KMT2A (0.42) | MAPTKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL4032286 | 0.83 | KMT2A (0.41) | MAPTKMT2AMEN1NPC1CCKBR | |
| SCHEMBL4032288 | 0.83 | KMT2A (0.41) | MAPTKMT2AMEN1NPC1CCKBR | |
| SCHEMBL4037079 | 0.82 | KMT2A (0.40) | MAPTKMT2ASMN1; SMN2MEN1PTGS2 | |
| SCHEMBL4037068 | 0.82 | KMT2A (0.40) | MAPTKMT2ASMN1; SMN2MEN1PTGS2 | |
| SCHEMBL4031864 | 0.81 | MAPT (0.40) | STING1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4034832 | 0.81 | MEN1 (0.39) | MAPTKMT2ASMN1; SMN2MEN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |