Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 3/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | NMBR | P28336 | 1/20 | 0.37 |
| ▸ | GRPR | P30550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942217 | 0.85 | MAPT (0.43) | MAPTSMN1; SMN2PTGS2HDAC8HDAC3 | |
| SCHEMBL4035462 | 0.84 | KMT2A (0.41) | MAPTPTGS2MEN1KMT2ANMBR | |
| SCHEMBL4038448 | 0.83 | KMT2A (0.42) | MAPTPTGS2MEN1KMT2ANMBR | |
| SCHEMBL4037073 | 0.82 | KMT2A (0.39) | MAPTMEN1KMT2ATACR1 | |
| SCHEMBL4031860 | 0.81 | STING1 (0.39) | MAPTSMN1; SMN2PTGS2HDAC8HDAC3 | |
| SCHEMBL4031866 | 0.81 | STING1 (0.39) | MAPTSMN1; SMN2PTGS2HDAC8HDAC3 | |
| SCHEMBL4033975 | 0.81 | MAPT (0.39) | MAPTMEN1KMT2ANMBRTACR1 | |
| SCHEMBL4034270 | 0.78 | KMT2A (0.46) | MAPTMEN1KMT2ANMBRPOLB | |
| SCHEMBL3947792 | 0.75 | MMP9 (0.43) | MAPTMEN1KMT2APOLBTACR1 | |
| SCHEMBL13904509 | 0.75 | MMP9 (0.43) | MAPTMEN1KMT2APOLBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |