⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035082 | 0.79 | — | — | |
| SCHEMBL57893 | 0.75 | — | — | |
| SCHEMBL28968854 | 0.72 | — | — | |
| SCHEMBL27563466 | 0.72 | — | — | |
| SCHEMBL694289 | 0.70 | — | — | |
| SCHEMBL19921 | 0.68 | — | — | |
| SCHEMBL161520 | 0.68 | — | — | |
| SCHEMBL3395205 | 0.68 | — | — | |
| SCHEMBL690348 | 0.68 | — | — | |
| SCHEMBL423990 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242945-B2 | Substituted 2-benzylidene-2H-benzo[b][1,4]thiazin-3(4H)-ones, derivatives thereof, and therapeutic uses thereof | Temple University—Of the Commonwealth System of Higher Education (US) | 2016-01-26 | — | — | US | claimed |
| CN-103228643-B | As the benzoxazole derivative of histamine h 4 receptor part | BIOPROJET (FR) | 2015-11-25 | — | — | CN | claimed |
| CN-102548970-B | Novel (6-oxo-1, 6-dihydropyrimidin-2-yl) amide derivatives, process for their preparation and their medical use as akt (pkb) phosphorylation inhibitors | SAI NUOFEI (FR) | 2015-11-25 | — | — | CN | claimed |
| US-20140086941-A1 | SUBSTITUTED 2-BENZYLIDENE-2H-BENZO[b][1,4]THIAZIN-3(4H)-ONES, DERIVATIVES THEREOF, AND THERAPEUTIC USES THEREOF | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2014-03-27 | — | — | US | claimed |
| WO-2012166586-A1 | SUBSTITUTED 2-BENZYLIDENE-2H-BENZO[b][1,4]THIAZIN-3(4H)-ONES, DERIVATIVES THEREOF, AND THERAPEUTIC USES THEREOF | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2012-12-06 | — | — | WO | claimed |
| EP-1513530-A4 | TETRAHYDROQUINOLINES FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | INTREXON CORP (US) | 2009-04-01 | — | — | EP | claimed |
| US-20050228016-A1 | TETRAHYDROQUINOLINES FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | MICHELOTTI ENRIQUE | 2005-10-13 | — | — | US | claimed |
| EP-1513530-A1 | TETRAHYDROQUINOLINES FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | RheoGene, Inc. (US) | 2005-03-16 | — | — | EP | claimed |
| EP-1474411-A2 | IMPROVED PROCESS FOR THE PRODUCTION OF DIHYDROPYRIDINES | Abbott Laboratories (US) | 2004-11-10 | — | — | EP | claimed |
| WO-2003105849-A1 | TETRAHYDROQUINOLINES FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | RHEOGENE, INC. (US) | 2003-12-24 | — | — | WO | claimed |
| WO-2003068765-A2 | IMPROVED PROCESS FOR THE PRODUCTION OF DIHYDROPYRIDINES | ABBOTT LABORATORIES (US) | 2003-08-21 | — | — | WO | claimed |
| US-20030153773-A1 | Process for the production of dihydropyridines | ABBOTT LABORATORIES | 2003-08-14 | — | — | US | claimed |
| EP-2948188-B1 | NEURONAL IMAGING AND TREATMENT | TYLERTON INT HOLDINGS INC (VG) | 2021-09-08 | — | — | EP | disclosed |
| CN-110520413-A | Big ring broad-spectrum antibiotic | RQX PHARMACEUTICALS INC | 2019-11-29 | — | — | CN | disclosed |
| CN-110267959-A | Imidazo [1,5-A ] pyrazine derivatives as PI3K delta inhibitors | 百济神州有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110072842-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2019-07-30 | — | — | CN | disclosed |
| EP-1474411-A2 | IMPROVED PROCESS FOR THE PRODUCTION OF DIHYDROPYRIDINES | Abbott Laboratories (US) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003105849-A1 | TETRAHYDROQUINOLINES FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | RHEOGENE, INC. (US) | 2003-12-24 | — | — | WO | disclosed |
| WO-2003068765-A2 | IMPROVED PROCESS FOR THE PRODUCTION OF DIHYDROPYRIDINES | ABBOTT LABORATORIES (US) | 2003-08-21 | — | — | WO | disclosed |
| US-20030153773-A1 | Process for the production of dihydropyridines | ABBOTT LABORATORIES | 2003-08-14 | — | — | US | disclosed |