⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694165 | 0.81 | — | — | |
| SCHEMBL58209 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL29140292 | 0.71 | — | — | |
| SCHEMBL694193 | 0.70 | — | — | |
| SCHEMBL4667815 | 0.70 | — | — | |
| SCHEMBL690348 | 0.70 | — | — | |
| SCHEMBL5095094 | 0.70 | — | — | |
| SCHEMBL3395205 | 0.70 | — | — | |
| SCHEMBL4032027 | 0.70 | — | — | |
| SCHEMBL5488868 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642918-B | Diosgenin derivative and preparation method and application thereof | 山东师范大学 | 2021-01-08 | — | — | CN | claimed |
| CN-110642918-A | Diosgenin derivative and preparation method and application thereof | 山东师范大学 | 2020-01-03 | — | — | CN | claimed |
| US-20160289217-A1 | COUMARIN BASED HSP90 INHIBITORS WITH UREA AND ETHER SUBSTITUENTS | UNIVERSITY OF KANSAS (US) | 2016-10-06 | — | — | US | claimed |
| US-20160272584-A1 | BIPHENYLAMIDE DERIVATIVE HSP90 INHIBITORS | UNIVERSITY OF KANSAS (US) | 2016-09-22 | — | — | US | claimed |
| EP-3068778-A2 | COUMARIN BASED HSP90 INHIBITORS WITH UREA AND ETHER SUBSTITUENTS | The University of Kansas (US) | 2016-09-21 | — | — | EP | claimed |
| EP-3066072-A1 | BIPHENYLAMIDE DERIVATIVE HSP90 INHIBITORS | The University of Kansas (US) | 2016-09-14 | — | — | EP | claimed |
| EP-2421852-B9 | HETEROAROMATIC AND AROMATIC PIPERAZINYL AZETIDINYL AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITOR | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |
| WO-2015070238-A2 | COUMARIN BASED HSP90 INHIBITORS WITH UREA AND ETHER SUBSTITUENTS | THE UNIVERSITY OF KANSAS (US) | 2015-05-14 | — | — | WO | claimed |
| WO-2015070091-A1 | BIPHENYLAMIDE DERIVATIVE HSP90 INHIBITORS | THE UNIVERSITY OF KANSAS (US) | 2015-05-14 | — | — | WO | claimed |
| CN-102548983-B | Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV | 2014-09-17 | — | — | CN | claimed |
| US-20030013718-A1 | Phthalazine derivatives for treating inflammatory diseases | NOVARTIS AG (CH) | 2003-01-16 | — | — | US | claimed |
| US-20020193608-A1 | Synthesis of [3,5,7]--1H-imidazo [1,5-a]imidazol-2 (3H)- one compounds | ELABDELLAOUI HASSAN M (US) | 2002-12-19 | — | — | US | claimed |
| CN-1367695-A | Phthalazine derivatives for the treatment of inflammatory diseases | NOVARTIS AG (CH) | 2002-09-04 | — | — | CN | claimed |
| US-6380210-B1 | USEFUL IN DIAGNOSIS AND TREATMENT OF ANXIETY, DOWN SYNDROME, SLEEP, COGNITIVE AND SEIZURE DISORDERS, DEPRESSION, OVERDOSE WITH BENZODIAZEPINE DRUGS, AND ENHANCEMENT OF MEMORY AND ALERTNESS | NEUROGEN CORPORATION | 2002-04-30 | — | — | US | claimed |
| US-6359144-B1 | BIOSYNTHESIS; SCREENING | LION BIOSCIENCE AG (DE) | 2002-03-19 | — | — | US | claimed |
| EP-1165085-A1 | PHTHALAZINE DERIVATIVES FOR TREATING INFLAMMATORY DISEASES | Novartis AG (CH) | 2002-01-02 | — | — | EP | claimed |
| WO-2000059509-A1 | PHTHALAZINE DERIVATIVES FOR TREATING INFLAMMATORY DISEASES | NOVARTIS AG (CH) | 2000-10-12 | — | — | WO | claimed |
| US-5856107-A | Combinatorial libraries of imidazol-pyrido-indole and imidazol-pyrido-benzothiophene derivatives, methods of making the libraries and compounds therein | TREGA BIOSCIENCES, INC. (US) | 1999-01-05 | — | — | US | claimed |
| WO-1998034113-A1 | COMBINATORIAL LIBRARIES OF BICYCLIC GUANIDINE DERIVATIVES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| WO-1998034112-A1 | COMBINATORIAL LIBRARIES OF IMIDAZOL-PYRIDO-INDOLES AND IMIDAZOL-PYRIDO-BENZOTHIOPHENE DERIVATIVES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |