Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 11/20 | 0.45 |
| ▸ | PPARG | P37231 | 10/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032530 | 0.93 | PPARG (0.52) | FFAR1PPARAPPARG | |
| SCHEMBL4035508 | 0.88 | FFAR1 (0.52) | FFAR1PPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL4032676 | 0.86 | PPARA (0.61) | FFAR1PPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL4028746 | 0.85 | PPARA (0.61) | FFAR1PPARAPPARGMAPTPOLB | |
| SCHEMBL4029556 | 0.84 | PPARG (0.55) | FFAR1PPARAPPARGMAPTPOLB | |
| SCHEMBL4025597 | 0.83 | FFAR1 (0.59) | FFAR1PPARAPPARGMAPTPOLB | |
| SCHEMBL4028592 | 0.83 | FFAR1 (0.52) | FFAR1PPARAPPARGMAPTPOLB | |
| SCHEMBL4034971 | 0.82 | FFAR1 (0.49) | FFAR1PPARAPPARGMAPTPOLB | |
| SCHEMBL4032694 | 0.82 | FFAR1 (0.49) | FFAR1PPARAPPARGMAPTPOLB | |
| SCHEMBL4027732 | 0.82 | FFAR1 (0.55) | FFAR1PPARAPPARGMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-B1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2009-01-07 | — | — | EP | claimed |