Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 10/20 | 0.47 |
| ▸ | PPARG | P37231 | 10/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034732 | 0.88 | FFAR1 (0.58) | FFAR1PPARAPPARGFAAHCES1 | |
| SCHEMBL4025597 | 0.86 | FFAR1 (0.59) | FFAR1PPARAPPARGMAPTPOLB | |
| SCHEMBL4032217 | 0.85 | FFAR1 (0.58) | FFAR1PPARAPPARGVDRPOLB | |
| SCHEMBL4032979 | 0.84 | FFAR1 (0.52) | FFAR1PPARAPPARGMAPTVDR | |
| SCHEMBL4028592 | 0.84 | FFAR1 (0.52) | FFAR1PPARAPPARGMAPTPOLB | |
| SCHEMBL4032676 | 0.84 | PPARA (0.61) | FFAR1PPARAPPARGMAPTPOLB | |
| SCHEMBL4029556 | 0.83 | PPARG (0.55) | FFAR1PPARAPPARGMAPTPOLB | |
| SCHEMBL4032708 | 0.83 | PPARG (0.63) | FFAR1PPARAPPARGPPARD | |
| SCHEMBL4028746 | 0.82 | PPARA (0.61) | FFAR1PPARAPPARGMAPTVDR | |
| SCHEMBL4032032 | 0.82 | FFAR1 (0.49) | FFAR1PPARAPPARGMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-B1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2009-01-07 | — | — | EP | claimed |