SCHEMBL4032082

SCHEMBL4032082

Cc1ccc(C=O)c(OCc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)n1

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.59
PPARG P37231 14/20 0.57
PPARA Q07869 11/20 0.57
KDR P35968 1/20 0.51
PTPN2 P17706 1/20 0.49
PTPN1 P18031 1/20 0.49
MAPT P10636 2/20 0.47
PPARD Q03181 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4034230 0.89 FFAR1 (0.58) FFAR1PPARGPPARAKDRPTPN2
SCHEMBL4032629 0.83 FFAR1 (0.64) FFAR1PPARGPPARAKDRMAPT
SCHEMBL4035331 0.83 FFAR1 (0.56) FFAR1PPARGPPARAKDRMAPT
SCHEMBL4845677 0.83 PPARG (0.56) FFAR1PPARGPPARAKDRPTPN2
SCHEMBL5377170 0.83 FFAR1 (0.54) FFAR1PPARGPPARAKDRPTPN2
SCHEMBL4032011 0.82 FFAR1 (0.70) FFAR1PPARGPPARAKDRPTPN2
SCHEMBL4851654 0.82 FFAR1 (0.53) FFAR1PPARGPPARAKDRPTPN2
SCHEMBL4745022 0.82 FFAR1 (0.70) FFAR1PPARGPPARAKDRMAPT
SCHEMBL4037251 0.82 FFAR1 (0.54) FFAR1PPARGPPARAKDRMAPT
SCHEMBL6157782 0.81 FFAR1 (0.65) FFAR1PPARGPPARAKDRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1357115-B1 ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF TAKEDA PHARMACEUTICAL (JP) 2009-06-17 EP disclosed
US-7238716-B2 Alkanoic acid derivatives process for their production and use thereof TAKEDA PHARMACEUTICALS COMPANY LIMITED (JP) 2007-07-03 US disclosed
US-20040058965-A1 Alkanoic acid derivatives process for their production and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-03-25 US disclosed
EP-1357115-A1 ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2003-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058965-A1 Alkanoic acid derivatives process for their production and use thereof GPR119, ACOX1, ALK FFAR1 4/4885PPARG 593/4885PPARA 156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.