Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 15/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029095 | 0.97 | ALDH1A1 (0.59) | SLC9A3ALDH1A1HPGDTSHR | |
| SCHEMBL4031751 | 0.90 | SLC9A3 (0.60) | SLC9A3 | |
| SCHEMBL4032540 | 0.90 | ALDH1A1 (0.48) | SLC9A3ALDH1A1HPGDTSHR | |
| SCHEMBL4036229 | 0.88 | ALDH1A1 (0.52) | SLC9A3ALDH1A1HPGDTSHR | |
| SCHEMBL4029992 | 0.86 | SLC9A3 (0.63) | SLC9A3ALDH1A1 | |
| SCHEMBL4031215 | 0.85 | SLC9A3 (0.62) | SLC9A3ALDH1A1 | |
| SCHEMBL4032895 | 0.84 | SLC9A3 (0.63) | SLC9A3 | |
| Cyclopropane SCHEMBL4034970 | 0.83 | SLC9A3 (0.66) | SLC9A3 | |
| SCHEMBL4026043 | 0.83 | SLC9A3 (0.66) | SLC9A3 | |
| Cyclopentane SCHEMBL4026133 | 0.83 | SLC9A3 (0.66) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453810-B1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AS MEDICAMENTS, IN ADDITION TO A MEDICAMENT CONTAINING SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-03-18 | — | — | EP | claimed |