Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2840832 | 1.00 | REN (0.67) | RENCYP3A4 | |
| SCHEMBL2840835 | 1.00 | REN (0.67) | RENCYP3A4 | |
| SCHEMBL3115470 | 0.95 | REN (0.67) | RENCYP3A4 | |
| SCHEMBL2850125 | 0.95 | REN (0.67) | RENCYP3A4 | |
| SCHEMBL2842466 | 0.95 | REN (0.67) | RENCYP3A4 | |
| SCHEMBL3111606 | 0.95 | REN (0.67) | RENCYP3A4 | |
| SCHEMBL3116302 | 0.95 | REN (0.67) | RENCYP3A4 | |
| SCHEMBL3114822 | 0.95 | REN (0.67) | RENCYP3A4 | |
| SCHEMBL3114550 | 0.95 | REN (0.67) | RENCYP3A4 | |
| SCHEMBL3111612 | 0.95 | REN (0.67) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010488-A2 | RENIN INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007117559-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |