Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | EDNRB | P24530 | 4/20 | 0.37 |
| ▸ | EDNRA | P25101 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030845 | 0.85 | PGR (0.46) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL4026159 | 0.84 | PGR (0.44) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL1336474 | 0.79 | PGR (0.69) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL6076049 | 0.79 | PGR (0.59) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL4030847 | 0.78 | PGR (0.50) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL4025581 | 0.78 | PGR (0.48) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL4026183 | 0.78 | PGR (0.41) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL4029566 | 0.78 | DRD3 (0.38) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL4031714 | 0.77 | PGR (0.44) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL4025576 | 0.77 | KCNH2 (0.41) | PGRADORA3CHRM1TBXA2RPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-B1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2009-01-07 | — | — | EP | claimed |