Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.63 |
| ▸ | PPARA | Q07869 | 15/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030505 | 0.94 | PPARG (0.64) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4029556 | 0.91 | PPARG (0.55) | PPARGPPARAFFAR1 | |
| SCHEMBL4034971 | 0.89 | FFAR1 (0.49) | PPARGPPARAFFAR1 | |
| SCHEMBL4032694 | 0.89 | FFAR1 (0.49) | PPARGPPARAFFAR1 | |
| SCHEMBL4030711 | 0.88 | PPARA (0.67) | PPARGPPARAFFAR1PPARDKDR | |
| SCHEMBL4032676 | 0.86 | PPARA (0.61) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4034248 | 0.84 | PPARG (0.61) | PPARGPPARAPPARD | |
| SCHEMBL4026131 | 0.84 | PPARG (0.61) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4032217 | 0.84 | FFAR1 (0.58) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4027732 | 0.83 | FFAR1 (0.55) | PPARGPPARAFFAR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-B1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2009-01-07 | — | — | EP | claimed |