Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026047 | 0.79 | PPARG (0.51) | PPARGCYP3A4RXRAPPARAPOLB | |
| SCHEMBL4025982 | 0.78 | PPARG (0.46) | PPARGCYP3A4RXRAPPARAPOLB | |
| SCHEMBL4025989 | 0.74 | PPARG (0.45) | PPARGCYP3A4RXRAPPARAFFAR1 | |
| SCHEMBL4026050 | 0.74 | PPARG (0.48) | PPARGCYP3A4RXRAPPARAFFAR1 | |
| SCHEMBL5803154 | 0.74 | PPARG (0.52) | PPARGCYP3A4RXRAPPARAFFAR1 | |
| SCHEMBL2332774 | 0.74 | PPARA (0.61) | PPARGPPARAPPARD | |
| SCHEMBL2361274 | 0.74 | PPARA (0.61) | PPARGPPARAPPARD | |
| SCHEMBL2332479 | 0.74 | PPARA (0.61) | PPARGPPARAPPARD | |
| SCHEMBL4026049 | 0.73 | PPARG (0.50) | PPARGCYP3A4RXRAPPARAMCHR1 | |
| SCHEMBL4031575 | 0.73 | PPARG (0.58) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-B1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2009-01-07 | — | — | EP | claimed |