SCHEMBL4032802

SCHEMBL4032802

CCOc1ccc(OCc2cccc(OCc3nc(-c4ccccc4)oc3C)c2)cc1CCC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.64
KDR P35968 1/20 0.60
PPARG P37231 17/20 0.56
PPARA Q07869 16/20 0.56
PPARD Q03181 3/20 0.54
CYP2C9 P11712 1/20 0.52
KCNH2 Q12809 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1744988 0.93 FFAR1 (0.64) FFAR1KDRPPARGPPARAPPARD
SCHEMBL4034348 0.93 FFAR1 (0.71) FFAR1KDRPPARGPPARAPPARD
SCHEMBL4031905 0.91 FFAR1 (0.70) FFAR1KDRPPARGPPARAPPARD
SCHEMBL4038285 0.90 FFAR1 (0.63) FFAR1KDRPPARGPPARAPPARD
SCHEMBL4029824 0.87 KDR (0.58) FFAR1KDRPPARGPPARACYP2C9
SCHEMBL4035777 0.86 FFAR1 (0.61) FFAR1KDRPPARGPPARAPPARD
SCHEMBL1747047 0.86 FFAR1 (0.71) FFAR1KDRPPARGPPARAPPARD
SCHEMBL12652902 0.85 FFAR1 (0.78) FFAR1KDRPPARGPPARACYP2C9
SCHEMBL4034751 0.85 FFAR1 (0.81) FFAR1KDRPPARGPPARAPPARD
SCHEMBL4035001 0.84 FFAR1 (0.62) FFAR1KDRPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1357115-B1 ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF TAKEDA PHARMACEUTICAL (JP) 2009-06-17 EP disclosed
US-7238716-B2 Alkanoic acid derivatives process for their production and use thereof TAKEDA PHARMACEUTICALS COMPANY LIMITED (JP) 2007-07-03 US disclosed
US-20040058965-A1 Alkanoic acid derivatives process for their production and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-03-25 US disclosed
EP-1357115-A1 ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2003-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058965-A1 Alkanoic acid derivatives process for their production and use thereof GPR119, ACOX1, ALK FFAR1 4/4885KDR 1328/4885PPARG 593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.