Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FDPS | P14324 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LPO | P22079 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515342 | 0.96 | — | — | |
| SCHEMBL173394 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL5446819 | 0.78 | MEN1 (0.41) | MEN1KMT2AFDPSTSHRLPO | |
| Bromide SCHEMBL27924357 | 0.78 | MEN1 (0.41) | MEN1KMT2AFDPSTSHRLPO | |
| SCHEMBL28233637 | 0.78 | MEN1 (0.39) | MEN1KMT2AFDPSTSHRLPO | |
| SCHEMBL6198920 | 0.77 | MEN1 (0.47) | MEN1KMT2AFDPSTSHRLPO | |
| Isopropyl Alcohol SCHEMBL29019954 | 0.77 | FDPS (0.41) | MEN1KMT2AFDPSTSHRLPO | |
| Acetic Acid SCHEMBL457852 | 0.75 | FDPS (0.43) | MEN1KMT2AFDPSTSHRLPO | |
| Sulfuric Acid SCHEMBL27895211 | 0.75 | FDPS (0.43) | MEN1KMT2AFDPSTSHRLPO | |
| SCHEMBL29769824 | 0.74 | MEN1 (0.41) | MEN1KMT2AFDPSTSHRLPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613613-A4 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2009-03-25 | — | — | EP | disclosed |
| EP-1613613-A2 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091518-A2 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2004-10-28 | — | — | WO | disclosed |