SCHEMBL40335

SCHEMBL40335

Nc1ncc(Cl)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5321375 0.73 MAP4K4 (0.67)
SCHEMBL5468823 0.73 MAP4K4 (0.52)
SCHEMBL4859450 0.72 MAP4K4 (0.56)
SCHEMBL149636 0.72
SCHEMBL2495212 0.72
SCHEMBL5500125 0.69 FGFR1 (0.46)
SCHEMBL24248969 0.67
SCHEMBL77304 0.67
SCHEMBL29787369 0.67
SCHEMBL15360097 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113549254-B Method for preparing modified vulcanized rubber and modified vulcanized rubber 中国科学技术大学 2022-10-28 CN claimed
CN-113549254-A Method for preparing modified vulcanized rubber and modified vulcanized rubber 中国科学技术大学 2021-10-26 CN claimed
EP-2074089-B1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2013-09-18 EP claimed
US-8222248-B2 Organic compounds NOVARTIS AG (CH) 2012-07-17 US claimed
US-20120148530-A1 Method for the treatment or prevention of virus infection using polybiguanide-based compounds NOVAFLUX BIOSCIENCES, INC. (US) 2012-06-14 US claimed
US-7772284-B2 Method for the treatment or prevention of virus infection using polybiguanide-based compounds NOVAFLUX INC. 2010-08-10 US claimed
US-7683097-B2 Topoisomerase inhibitors Propharmacon Inc. (US) 2010-03-23 US claimed
EP-1654260-A4 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS PFIZER PROD INC (US) 2008-09-24 EP claimed
EP-1654260-A2 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS Pfizer Products Inc. (US) 2006-05-10 EP claimed
US-20050107381-A1 6-membered heteroaryl compounds for the treatment of neurodegenerative disorders PFIZER, INC. 2005-05-19 US claimed
WO-2005011601-A2 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS PFIZER PRODUCTS, INC. (US) 2005-02-10 WO claimed
EP-1140931-A1 5HT1 ANTAGONISTS FOR ANTIDEPRESSANT THERAPY Pfizer Products Inc. (US) 2001-10-10 EP claimed
WO-2000039128-A1 5HT1 ANTAGONISTS FOR ANTIDEPRESSANT THERAPY PFIZER PRODUCTS INC. (US) 2000-07-06 WO claimed
EP-4719392-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Tenvie Therapeutics Inc. (US) 2026-04-08 EP disclosed
US-20260008780-A1 SUBSTITUTED 3,4-DIHYDROISOQUINOLIN-1(2H)-ONE DERIVATIVES AND RELATED USES NODTHERA LTD (GB) 2026-01-08 US disclosed
US-20250388603-A1 ANTIMALARIAL COMPOUNDS SCRIPPS RESEARCH INST (US) 2025-12-25 US disclosed
US-4342587-A Herbicidal pyridinsulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-08-03 US disclosed
EP-0029282-A1 Process for preparing 5-halopyrimidines and 5-pyrimidine methanols ELI LILLY AND COMPANY (US) 1981-05-27 EP disclosed
US-4252955-A FROM 4-HALO-5-HYDROXY-2(5H)-FURANONES AND FORMAMIDE AT HIGH TEMPERATURE ELI LILLY AND COMPANY (US) 1981-02-24 US disclosed
EP-0023140-A2 Herbicidal sulfonamides, preparation and use thereof, and compositions containing them E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-28 EP disclosed