SCHEMBL77304

SCHEMBL77304

Nc1ccc(Cl)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29787369 1.00
SCHEMBL29505989 0.97
Methylene Chloride SCHEMBL18894823 0.93 LTA4H (0.48)
Alcohol SCHEMBL28161473 0.87 MAP4K4 (0.46)
Acetic Acid SCHEMBL7838974 0.85 GABRP (0.52)
SCHEMBL30509801 0.82
SCHEMBL312830 0.80 LTA4H (0.79)
Butyl Alcohol SCHEMBL28142145 0.79 NPC1 (0.43)
SCHEMBL9579908 0.78 ADRA2A (0.46)
SCHEMBL11405655 0.75 RXFP1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3707 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4631932-A1 PREPARATION METHOD FOR EDOXABAN AND INTERMEDIATE THEREOF Zhejiang Huahai Pharmaceutical Co., Ltd. (CN) 2025-10-15 EP claimed
CN-119432148-A Perovskite ink, perovskite film and battery device 云南大学 2025-02-14 CN claimed
CN-114685448-B Synthesis method of zopiclone impurity pyrazine-2-carboxylic acid (5-chloro-pyridine-2-yl) -amide 江苏天士力帝益药业有限公司 2025-01-07 CN claimed
CN-118724801-B Preparation method of intermediate of toluene sulfonic acid Ai Duosha class 中节能万润股份有限公司 2024-12-03 CN claimed
CN-118812530-A Method for preparing imidazole pyridine compound by catalyzing lignin and model compound by Pd/C bi-component system 中国科学院大连化学物理研究所 2024-10-22 CN claimed
CN-118724801-A Preparation method of intermediate of toluene sulfonic acid Ai Duosha class 中节能万润股份有限公司 2024-10-01 CN claimed
WO-2024120275-A1 PREPARATION METHOD FOR EDOXABAN AND INTERMEDIATE THEREOF 浙江华海药业股份有限公司 2024-06-13 WO claimed
CN-118146145-A Preparation method of ideoxaban and intermediate thereof 浙江华海药业股份有限公司 2024-06-07 CN claimed
CN-116354900-B Chlorothiazole compound containing maleic acid structure, and preparation method and application thereof 中国农业大学 2024-03-12 CN claimed
CN-117192014-A Detection method of eszopiclone isomer 湖南省药品检验检测研究院 2023-12-08 CN claimed
US-6673811-B1 TREATMENT OF ANXIETY, DEPRESSION, SLEEP DISORDER, ATTENTION DEFICIT DISORDER, ALZHEIMER'S DEMENTIA, OR SHORT-TERM MEMORY LOSS NEUROGEN CORPORATION 2004-01-06 US claimed
WO-2003099276-A1 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-12-04 WO claimed
EP-1325006-A2 HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABA A? RECEPTOR NEUROGEN CORPORATION (US) 2003-07-09 EP claimed
US-20030105081-A1 Heterocyclic compounds as ligands of the GABAA receptor PFIZER INC 2003-06-05 US claimed
WO-2003044018-A1 1H-PYRROLO[3,2-B]PYRIDINE-3-CARBOXYLIC ACID AMIDES NEUROGEN CORPORATION (US) 2003-05-30 WO claimed
WO-2002028353-A2 PHOSPHATE TRANSPORT INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2002-04-11 WO claimed
WO-2002012442-A2 HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABAA RECEPTOR NEUROGEN CORPORATION (US) 2002-02-14 WO claimed
EP-0331052-A2 Process for the preparation of imidized acrylic polymers ELF ATOCHEM ITALIA S.r.l. (IT) 1989-09-06 EP claimed
US-4212870-A 1-(2,6-Dichlorobenzoyl)-3-(5-chloro-2-pyridinyl-N-oxide)urea and use as insecticide GULF OIL CORPORATION (US) 1980-07-15 US claimed
US-3985759-A Process for preparing 2-amino-5-chloropyridine ELI LILLY AND COMPANY (US) 1976-10-12 US claimed