Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PREP | P48147 | 3/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27700641 | 0.99 | TMEM97 (0.67) | TMEM97SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| Water SCHEMBL27740102 | 0.97 | TMEM97 (0.66) | TMEM97SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| Water SCHEMBL27760581 | 0.92 | TMEM97 (0.63) | TMEM97SIGMAR1PREPFKBP1A | |
| SCHEMBL5474103 | 0.91 | TMEM97 (0.65) | TMEM97SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30145608 | 0.90 | TMEM97 (0.64) | TMEM97SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27924857 | 0.89 | TMEM97 (0.63) | TMEM97SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5456476 | 0.89 | SIGMAR1 (0.63) | TMEM97SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27924834 | 0.88 | TMEM97 (0.62) | TMEM97SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4122759 | 0.87 | TMEM97 (0.60) | TMEM97SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2379314 | 0.87 | TMEM97 (0.60) | TMEM97SIGMAR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501467-A4 | HETEROCYCLO INHIBITORS OF POTASSIUM CHANNEL FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2009-08-19 | — | — | EP | disclosed |
| CN-101501020-A | Nitrate esters of piperidines | SPEEDEL EXPERIMENTA AG (CH) | 2009-08-05 | — | — | CN | disclosed |
| CN-101151247-A | 3,4, 5-substituted piperidines as renin inhibitors | SPEEDEL EXPERIMENTA AG (CH) | 2008-03-26 | — | — | CN | disclosed |
| CN-101151263-A | Substituted piperidines as renin inhibitors | SPEEDEL EXPERIMENTA AG (CH) | 2008-03-26 | — | — | CN | disclosed |
| EP-1501467-A2 | HETEROCYCLO INHIBITORS OF POTASSIUM CHANNEL FUNCTION | Bristol-Myers Squibb Company (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003088908-A2 | HETEROCYCLO INHIBITORS OF POTASSIUM CHANNEL FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-10-30 | — | — | WO | disclosed |