Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289058 | 1.00 | GRIN2B (0.57) | GRIN2BENPP2PTGS2GAARAB9A | |
| SCHEMBL1338333 | 0.82 | CA2 (0.61) | PTGS2 | |
| SCHEMBL1338332 | 0.82 | CA2 (0.61) | PTGS2 | |
| SCHEMBL2772513 | 0.82 | CA2 (0.61) | PTGS2 | |
| SCHEMBL13153888 | 0.79 | GAA (0.40) | GRIN2BGAARAB9AKDM1AALDH1A1 | |
| SCHEMBL13153894 | 0.79 | SMN1; SMN2 (0.47) | GAAALDH1A1 | |
| SCHEMBL26181143 | 0.79 | SMN1; SMN2 (0.50) | GRIN2BGAARAB9AKDM1AALDH1A1 | |
| SCHEMBL9968918 | 0.78 | AURKA (0.48) | GRIN2BGAAKDM1AALDH1A1 | |
| SCHEMBL29478780 | 0.78 | AURKA (0.48) | GRIN2BGAAKDM1AALDH1A1 | |
| SCHEMBL410486 | 0.78 | AURKA (0.48) | GRIN2BGAAKDM1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013201-A1 | HETEROCYCLIC GPCR AGONISTS | Prosidion Limited (GB) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007116229-A1 | HETEROCYCLIC GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-10-18 | — | — | WO | disclosed |
| EP-1613304-B1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS CH (CH) | 2007-09-12 | — | — | EP | disclosed |
| WO-2001054507-A1 | METHODS FOR KILLING NEMATODES AND NEMATODE EGGS USING OXADIAZOLE AND OXAIMIDAZOLE COMPOUNDS | AKKADIX CORPORATION (US) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001002375-A1 | PROCESS FOR SYNTHESIZING OXADIAZOLES | CHEMRX ADVANCED TECHNOLOGIES, INC. (US) | 2001-01-11 | — | — | WO | disclosed |