Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 8/20 | 0.34 |
| ▸ | GLS | O94925 | 2/20 | 0.31 |
| ▸ | HTRA1 | Q92743 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4479717 | 0.79 | F10 (0.55) | F10 | |
| SCHEMBL4033308 | 0.79 | F10 (0.55) | F10 | |
| SCHEMBL4030621 | 0.68 | F10 (0.63) | SMN1; SMN2F10 | |
| SCHEMBL4033672 | 0.68 | F10 (0.63) | SMN1; SMN2F10 | |
| SCHEMBL6180572 | 0.66 | MCHR1 (0.43) | — | |
| SCHEMBL13754450 | 0.58 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAMAPK1KMT2A | |
| SCHEMBL3426918 | 0.57 | F2 (0.53) | SMN1; SMN2F10LMNAMAPK1KMT2A | |
| SCHEMBL8156583 | 0.57 | MIF (0.41) | F10LMNA | |
| SCHEMBL23111328 | 0.55 | SMN1; SMN2 (0.41) | SMN1; SMN2F10LMNAMAPK1KMT2A | |
| SCHEMBL20600952 | 0.55 | SMN1; SMN2 (0.59) | SMN1; SMN2F10LMNAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562939-B1 | CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2009-01-21 | — | — | EP | claimed |