Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379964 | 0.83 | CYP2D6 (0.47) | MCHR1NPSR1KDM4EAAK1 | |
| SCHEMBL4479717 | 0.78 | F10 (0.55) | — | |
| SCHEMBL4033308 | 0.78 | F10 (0.55) | — | |
| SCHEMBL4033674 | 0.66 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL20679611 | 0.62 | GSTO1 (0.63) | NPSR1KDM4EEPHX2GSTO1 | |
| SCHEMBL30675599 | 0.62 | GSTO1 (0.63) | NPSR1KDM4EEPHX2GSTO1 | |
| SCHEMBL6181130 | 0.61 | F10 (0.66) | GSTO1 | |
| SCHEMBL1377310 | 0.61 | F10 (0.61) | KDM4EBACE2 | |
| SCHEMBL5873685 | 0.61 | MCHR1 (0.59) | MCHR1EPHX2 | |
| SCHEMBL7873626 | 0.61 | NPSR1 (0.57) | MCHR1NPSR1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562939-A1 | CARBOXAMIDES | MERCK PATENT GmbH (DE) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046138-A1 | CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2004-06-03 | — | — | WO | disclosed |