SCHEMBL4033776

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13797844	0.93	RET (0.64)	RETCDK1ERBB2KDRFGFR1
	SCHEMBL4039682	0.86	RET (0.55)	RETCDK1ERBB2KDR
	SCHEMBL4038630	0.84	RET (0.65)	RETCDK1ERBB2KDRAURKA
	SCHEMBL4038471	0.84	RET (0.52)	RETCDK1ERBB2KDRFGFR1
	SCHEMBL4033805	0.83	RET (0.53)	RETCDK1ERBB2KDRFGFR1
	Methylethylamine SCHEMBL5821868	0.83	MAP3K8 (0.55)	RETCDK1ERBB2KDR
	SCHEMBL4034563	0.83	CDK1 (0.66)	RETCDK1ERBB2KDR
	SCHEMBL4039564	0.83	RET (0.66)	RETCDK1ERBB2KDRAURKA
	SCHEMBL4035297	0.82	RET (0.68)	RETCDK1ERBB2KDRAURKA
	Ethylamine SCHEMBL5823397	0.82	RET (0.62)	RETCDK1ERBB2KDRAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.