Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | LIG1 | P18858 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | RHOA | P61586 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034461 | 0.89 | CYP3A4 (0.72) | CYP3A4HSD17B10ALDH1A1TSHRLIG1 | |
| SCHEMBL12904274 | 0.86 | CYP3A4 (0.68) | CYP3A4HSD17B10ALDH1A1TSHRLIG1 | |
| SCHEMBL4629655 | 0.86 | CYP3A4 (0.68) | CYP3A4HSD17B10ALDH1A1TSHRLIG1 | |
| SCHEMBL10538212 | 0.84 | CYP3A4 (0.74) | CYP3A4HSD17B10ALDH1A1TSHRLIG1 | |
| SCHEMBL174686 | 0.84 | CYP3A4 (0.74) | CYP3A4HSD17B10ALDH1A1TSHRLIG1 | |
| SCHEMBL8169878 | 0.84 | CYP3A4 (0.64) | CYP3A4HSD17B10ALDH1A1TSHRLIG1 | |
| SCHEMBL7512172 | 0.84 | CYP3A4 (0.64) | CYP3A4HSD17B10ALDH1A1TSHRLIG1 | |
| Bicarbonate SCHEMBL20838538 | 0.83 | CYP3A4 (0.92) | CYP3A4HSD17B10ALDH1A1TSHRLIG1 | |
| SCHEMBL6270169 | 0.83 | CYP3A4 (0.59) | CYP3A4HSD17B10ALDH1A1TSHRLIG1 | |
| SCHEMBL11121490 | 0.83 | CYP3A4 (0.68) | CYP3A4HSD17B10ALDH1A1TSHRLIG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2052009-B1 | METHOD OF PREPARING POLYCARBONATE | SABIC INNOVATIVE PLASTICS IP (NL) | 2012-12-19 | — | — | EP | disclosed |
| CN-101641392-A | Polycarbonate and method for producing same | GEN ELECTRIC NL | 2010-02-03 | — | — | CN | disclosed |
| EP-2074160-A2 | POLYCARBONATES AND METHOD OF PREPARING SAME | Sabic Innovative Plastics IP B.V. (NL) | 2009-07-01 | — | — | EP | disclosed |
| EP-2052009-A1 | METHOD OF PREPARING POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2009-04-29 | — | — | EP | disclosed |
| US-7498400-B2 | Method of preparing polycarbonate | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-03-03 | — | — | US | disclosed |
| US-7482423-B2 | Polycarbonates and method of preparing same | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-01-27 | — | — | US | disclosed |
| WO-2008005623-A2 | POLYCARBONATES AND METHOD OF PREPARING SAME | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-01-10 | — | — | WO | disclosed |
| WO-2008005648-A1 | METHOD OF PREPARING POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2008-01-10 | — | — | WO | disclosed |
| US-20080004418-A1 | Reacting dihydroxy compound with an activated diaryl carbonate in the presence of an esterification catalyst to produce a polycarbonate, wherein the carbonate reaction component and the dihydroxy reaction component are reacted in the presence of a monofunctional chainstopper; color, hydrolytic stability | GENERAL ELECTRIC COMPANY (US) | 2008-01-03 | — | — | US | disclosed |
| US-20080004417-A1 | Polycarbonates and method of preparing same | GENERAL ELECTRIC COMPANY (US) | 2008-01-03 | — | — | US | disclosed |