SCHEMBL6270169

SCHEMBL6270169

C=CCOC(=O)c1ccccc1OC(=O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.59
HSD17B10 Q99714 2/20 0.52
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.52
SLC6A3 Q01959 1/20 0.50
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44
ADRB3 P13945 1/20 0.44
KDM4E B2RXH2 2/20 0.43
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
SNCA P37840 1/20 0.42
KMT2A Q03164 2/20 0.41
PRSS1 P07477 2/20 0.41
ACR P10323 2/20 0.41
MEN1 O00255 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2346908 0.84 CYP3A4 (0.61) CYP3A4HSD17B10ALDH1A1TSHRKDM4E
SCHEMBL4034459 0.83 CYP3A4 (0.70) CYP3A4HSD17B10ALDH1A1TSHRSLC6A3
SCHEMBL4034461 0.82 CYP3A4 (0.72) CYP3A4HSD17B10ALDH1A1TSHRSLC6A3
SCHEMBL8169878 0.80 CYP3A4 (0.64) CYP3A4HSD17B10ALDH1A1TSHRADRB2
SCHEMBL12904274 0.79 CYP3A4 (0.68) CYP3A4HSD17B10ALDH1A1TSHRSLC6A3
SCHEMBL4629655 0.79 CYP3A4 (0.68) CYP3A4HSD17B10ALDH1A1TSHRADRB2
SCHEMBL4072700 0.79 CYP3A4 (0.72) CYP3A4HSD17B10ALDH1A1TSHRSLC6A3
SCHEMBL9360315 0.78 CYP3A4 (0.62) CYP3A4HSD17B10ALDH1A1TSHRADRB2
SCHEMBL461801 0.78 SNCA (0.61) CYP3A4HSD17B10ALDH1A1TSHRADRB2
Terephthalic Acid SCHEMBL27490081 0.77 CYP3A4 (0.80) CYP3A4HSD17B10ALDH1A1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005019156-A2 BIPHENYL-4-CARBOXYLIC ACID ALKYLOXYCARBONYL PHENYL ESTERS AND USES THEREOF THE UNIVERSITY OF HULL (GB) 2005-03-03 WO disclosed