Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034108 | 0.91 | LPAR1 (0.44) | LPAR1LPAR3LPAR2MEN1KMT2A | |
| SCHEMBL4034159 | 0.90 | LPAR1 (0.44) | LPAR1LPAR3LPAR2MEN1KMT2A | |
| SCHEMBL4032925 | 0.89 | LPAR1 (0.42) | LPAR1LPAR3LPAR2MEN1KMT2A | |
| SCHEMBL4029083 | 0.89 | LPAR1 (0.48) | LPAR1LPAR3LPAR2MEN1KMT2A | |
| SCHEMBL4033264 | 0.89 | LPAR1 (0.40) | LPAR1LPAR3LPAR2MEN1KMT2A | |
| SCHEMBL4034918 | 0.89 | LPAR1 (0.45) | LPAR1LPAR3LPAR2S1PR1S1PR3 | |
| SCHEMBL4030949 | 0.88 | LPAR1 (0.53) | LPAR1LPAR3LPAR2MEN1KMT2A | |
| SCHEMBL15437576 | 0.88 | LPAR1 (0.43) | LPAR1LPAR3LPAR2MEN1KMT2A | |
| SCHEMBL4032476 | 0.88 | LPAR1 (0.43) | LPAR1LPAR3LPAR2MEN1KMT2A | |
| SCHEMBL4029159 | 0.88 | LPAR1 (0.47) | LPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258484-B1 | NOVEL ISOXAZOLE AND THIAZOLE COMPOUNDS AND USE THEREOF AS DRUGS | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-01-14 | — | — | EP | claimed |