SCHEMBL4034700

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5656833	0.91	TGFBR1 (0.53)	TGFBR1MAPK14MAPTALDH1A1LMNA
	SCHEMBL4035152	0.89	TGFBR1 (0.49)	TGFBR1MAPK14TGFBR2MAP3K20SLC9A1
	SCHEMBL4032798	0.83	TGFBR1 (0.71)	TGFBR1MAPK14MAPTALDH1A1LMNA
	SCHEMBL5695716	0.83	TGFBR1 (0.67)	TGFBR1MAPK14MAPTALDH1A1LMNA
	SCHEMBL4029479	0.81	TGFBR1 (0.43)	TGFBR1MAPK14TGFBR2MAP3K20SLC9A1
	SCHEMBL4030303	0.80	TGFBR1 (0.39)	TGFBR1MAPK14MAPK1TGFBR2MAP3K20
	SCHEMBL4035145	0.78	TGFBR1 (1.00)	TGFBR1MAPK14
	SCHEMBL5695772	0.78	TGFBR1 (0.48)	TGFBR1MAPK14MAPTALDH1A1LMNA
	SCHEMBL5695727	0.78	TGFBR1 (0.64)	TGFBR1MAPK14MAPTALDH1A1LMNA
	SCHEMBL4030670	0.77	TGFBR1 (0.41)	TGFBR1MAPK14TGFBR2MAP3K20SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.