Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | SI | P14410 | 4/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034815 | 1.00 | ALOX5 (0.46) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4028884 | 0.88 | ALOX5 (0.47) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4028875 | 0.88 | ALOX5 (0.47) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4039237 | 0.85 | ALOX5 (0.44) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4039229 | 0.85 | ALOX5 (0.44) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4034574 | 0.84 | ALOX5 (0.47) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4034578 | 0.84 | ALOX5 (0.47) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4034396 | 0.83 | ALOX5 (0.44) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4031059 | 0.83 | ALOX5 (0.46) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4031055 | 0.83 | ALOX5 (0.46) | ALOX5EPHX2CDK4CCND1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |