Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034832 | 1.00 | MEN1 (0.39) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL4035465 | 0.86 | KMT2A (0.42) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL4035456 | 0.86 | KMT2A (0.42) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL4032288 | 0.85 | KMT2A (0.41) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL4032286 | 0.85 | KMT2A (0.41) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL3938457 | 0.85 | MAPT (0.39) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL13961580 | 0.85 | MAPT (0.39) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL4037079 | 0.84 | KMT2A (0.40) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL4037068 | 0.84 | KMT2A (0.40) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL4034396 | 0.84 | ALOX5 (0.44) | MEN1KMT2AMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |