Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.47 |
| ▸ | MMP9 | P14780 | 5/20 | 0.47 |
| ▸ | MMP3 | P08254 | 4/20 | 0.47 |
| ▸ | MMP7 | P09237 | 4/20 | 0.47 |
| ▸ | MMP13 | P45452 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5634717 | 0.92 | GAA (0.46) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL5634849 | 0.86 | MMP1 (0.52) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL4038558 | 0.84 | MMP1 (0.51) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL5634718 | 0.82 | HCRTR1 (0.47) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL5635564 | 0.79 | MMP1 (0.51) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL5635339 | 0.76 | MMP1 (0.50) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL4032820 | 0.76 | GAA (0.49) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL4035214 | 0.76 | MAPT (0.46) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL5635556 | 0.74 | MMP1 (0.53) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL4033302 | 0.72 | MMP1 (0.48) | MMP1MMP9MMP3MMP7MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |