SCHEMBL4035542

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4035544	1.00	PIK3CG (0.62)	PIK3CGIGF1RTTRNAT1PIM1
	SCHEMBL4198477	1.00	PIK3CG (0.62)	PIK3CGIGF1RTTRNAT1PIM1
	SCHEMBL1247522	0.88	PIM1 (0.72)	PIK3CGIGF1RTTRNAT1PIM1
	SCHEMBL1247523	0.88	PIM1 (0.72)	PIK3CGIGF1RTTRNAT1PIM1
	SCHEMBL6927233	0.82	IGF1R (0.60)	PIK3CGIGF1RTTRNAT1PIM1
	SCHEMBL6927235	0.82	IGF1R (0.60)	PIK3CGIGF1RTTRNAT1PIM1
	SCHEMBL4035316	0.82	PIM1 (0.64)	PIK3CGIGF1RNAT1PIM1AKR1B1
	SCHEMBL4035319	0.82	PIM1 (0.64)	PIK3CGIGF1RNAT1PIM1AKR1B1
	SCHEMBL4206382	0.82	PIM1 (0.64)	PIK3CGIGF1RNAT1PIM1AKR1B1
	SCHEMBL1247443	0.82	PIM1 (0.62)	IGF1RTTRNAT1PIM1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.