Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 18/20 | 0.51 |
| ▸ | BRAF | P15056 | 18/20 | 0.51 |
| ▸ | FLT1 | P17948 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032272 | 0.92 | KIT (0.47) | KITBRAFFLT1KDR | |
| SCHEMBL3878184 | 0.88 | KIT (0.62) | KITBRAFFLT1KDR | |
| SCHEMBL3868747 | 0.87 | KIT (0.60) | KITBRAFFLT1KDR | |
| SCHEMBL3870092 | 0.85 | FLT1 (0.48) | KITBRAFFLT1KDR | |
| SCHEMBL4032270 | 0.84 | KIT (0.53) | KITBRAFFLT1KDR | |
| SCHEMBL4037571 | 0.84 | KIT (0.50) | KITBRAFFLT1KDR | |
| SCHEMBL4042755 | 0.83 | NPC1 (0.52) | KITBRAFFLT1KDR | |
| SCHEMBL4042245 | 0.81 | FLT1 (0.42) | KITBRAFFLT1KDR | |
| SCHEMBL13875588 | 0.79 | FLT1 (0.50) | KITBRAFFLT1KDR | |
| SCHEMBL3866845 | 0.79 | FLT1 (0.50) | KITBRAFFLT1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392680-B1 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | BAYER SCHERING PHARMA AG (DE) | 2009-07-22 | — | — | EP | disclosed |
| EP-1392680-A2 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090352-A2 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-11-14 | — | — | WO | disclosed |