Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | GRM7 | Q14831 | 5/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.39 |
| ▸ | TUBB | P07437 | 4/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4210193 | 0.84 | GRM7 (0.41) | ERN1GRM7TUBB4ATUBBTUBA3C | |
| SCHEMBL4212113 | 0.83 | GRM7 (0.42) | GRM7TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4036659 | 0.82 | ERN1 (0.41) | ERN1GRM7TUBB4ATUBBTUBA3C | |
| SCHEMBL15225913 | 0.80 | ERN1 (0.50) | ERN1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4211203 | 0.78 | TUBB4A (0.44) | ERN1GRM7TUBB4ATUBBTUBA3C | |
| SCHEMBL4209454 | 0.76 | TUBB4A (0.40) | ERN1GRM7TUBB4ATUBBTUBA3C | |
| SCHEMBL4036088 | 0.76 | GRM7 (0.38) | GRM7TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4218244 | 0.76 | GRM7 (0.39) | ERN1GRM7TUBB4ATUBBTUBA3C | |
| SCHEMBL4221208 | 0.76 | TUBB4A (0.41) | ERN1GRM7TUBB4ATUBBTUBA3C | |
| SCHEMBL4214918 | 0.76 | TUBB4A (0.41) | GRM7TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | Chong Kun Dang Pharmaceutical Corp. (KR) | 2009-06-10 | — | — | EP | claimed |
| WO-2008038955-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-04-03 | — | — | WO | claimed |