Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 8/20 | 0.48 |
| ▸ | CNR2 | P34972 | 8/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 6/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039498 | 1.00 | PPARG (0.50) | PPARGCNR1CNR2GPR55BCHE | |
| SCHEMBL3340894 | 1.00 | PPARG (0.50) | PPARGCNR1CNR2GPR55BCHE | |
| SCHEMBL4034678 | 0.97 | PPARG (0.49) | PPARGCNR1CNR2GPR55BCHE | |
| SCHEMBL4036191 | 0.97 | PPARG (0.49) | PPARGCNR1CNR2GPR55BCHE | |
| SCHEMBL13648968 | 0.97 | PPARG (0.49) | PPARGCNR1CNR2GPR55BCHE | |
| SCHEMBL4042000 | 0.94 | PPARG (0.51) | PPARGCNR1CNR2GPR55ABCG2 | |
| SCHEMBL13654317 | 0.89 | ALOX5 (0.49) | CNR1CNR2GPR55ABCG2GPR18 | |
| SCHEMBL13654240 | 0.87 | ALOX5 (0.51) | ABCG2ALOX5 | |
| SCHEMBL13654327 | 0.87 | ALOX5 (0.51) | ABCG2ALOX5 | |
| SCHEMBL13654297 | 0.87 | ALOX5 (0.51) | ABCG2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601754-B2 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2009-10-13 | — | — | US | disclosed |
| US-7601754-B2 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2009-10-13 | — | — | US | disclosed |
| US-7601754-B2 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2009-10-13 | — | — | US | disclosed |
| EP-1534698-B1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | ROWETT RES INST (GB) | 2007-09-19 | — | — | EP | disclosed |
| EP-1534698-B1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | ROWETT RES INST (GB) | 2007-09-19 | — | — | EP | disclosed |
| US-20060137207-A1 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2006-06-29 | — | — | US | disclosed |
| EP-1534698-A1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | The Rowett Research Institute (GB) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004007475-A1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | ROWETT RESEARCH INSTITUTE (GB) | 2004-01-22 | — | — | WO | disclosed |