SCHEMBL4036044

SCHEMBL4036044

CCC(c1nc2onc(C)c2c(=O)n1Cc1ccccc1)N(CCCNC(=O)O)S(=O)(=O)c1cccc(C)c1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4037115 0.94 KIF11 (0.57) KIF11
SCHEMBL4043120 0.92 KIF11 (0.61) KIF11
SCHEMBL4039799 0.90 KIF11 (0.55) KIF11
SCHEMBL4042910 0.90 KIF11 (0.64) KIF11
SCHEMBL4037105 0.89 KIF11 (0.56) KIF11
SCHEMBL4044398 0.88 KIF11 (0.53) KIF11
SCHEMBL5787665 0.86 KIF11 (0.52) KIF11
SCHEMBL4044119 0.85 KIF11 (0.71) KIF11
SCHEMBL4037849 0.84 KIF11 (0.67) KIF11
SCHEMBL4038319 0.82 KIF11 (0.71) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1601673-B1 FUSED HETEROCYCLES AND USES THEREOF ASTRAZENECA AB (SE) 2009-06-10 EP claimed
EP-1601673-B1 FUSED HETEROCYCLES AND USES THEREOF ASTRAZENECA AB (SE) 2009-06-10 EP disclosed