Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041101 | 0.91 | KIF11 (0.63) | KIF11 | |
| SCHEMBL4040565 | 0.91 | KIF11 (0.76) | KIF11 | |
| SCHEMBL4038230 | 0.90 | KIF11 (0.79) | KIF11 | |
| SCHEMBL4038608 | 0.88 | KIF11 (0.67) | KIF11 | |
| SCHEMBL4036121 | 0.88 | KIF11 (0.76) | KIF11 | |
| SCHEMBL5739693 | 0.88 | KIF11 (0.83) | KIF11 | |
| SCHEMBL4046092 | 0.88 | KIF11 (0.62) | KIF11 | |
| SCHEMBL4038393 | 0.88 | KIF11 (0.72) | KIF11 | |
| SCHEMBL4036341 | 0.88 | KIF11 (0.75) | KIF11 | |
| SCHEMBL4037064 | 0.88 | KIF11 (0.66) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601673-B1 | FUSED HETEROCYCLES AND USES THEREOF | ASTRAZENECA AB (SE) | 2009-06-10 | — | — | EP | claimed |
| EP-1601673-B1 | FUSED HETEROCYCLES AND USES THEREOF | ASTRAZENECA AB (SE) | 2009-06-10 | — | — | EP | disclosed |
| EP-1230243-B1 | POYCYLOALKYLPURINES AS ADENOSINE RECEPTOR ANTAGONISTS | BIOGEN IDEC INC (US) | 2009-03-04 | — | — | EP | disclosed |