Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 8/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PPARD | Q03181 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | FABP2 | P12104 | 1/20 | 0.54 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045831 | 0.94 | PPARA (0.69) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL4033102 | 0.89 | PPARA (0.62) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL9416379 | 0.87 | PPARA (0.65) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL4033955 | 0.84 | MAP4K4 (0.54) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL8264617 | 0.84 | PPARA (0.55) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL6350219 | 0.84 | PPARA (0.89) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL1305108 | 0.82 | PPARA (0.54) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL11545612 | 0.80 | PPARA (0.71) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL3485018 | 0.80 | PPARA (0.69) | PPARACYP1A2CYP3A4PPARGTSHR | |
| SCHEMBL4033331 | 0.80 | PPARA (0.66) | PPARAMEN1KMT2ACYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |